华夏棋牌

二价、四价、九价,HPV疫苗该如何选择?

2018-06-22  来自: 商丘市公安法医医院HPV科 浏览次数:69

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华夏棋牌SHOUXIANYAOMINGQUEYIGEGAINIAN:HPVYIMIAOSHI“RENRUTOULIUBINGDUYIMIAO”,ERBUSHI“GONGJINGAIYIMIAO”。HPVSHI“RENRUTOULIUBINGDU”DEYISI,HPVYIMIAOSHIYUFANGHPVXIANGGUANJIBINGDE,HPVXIANGGUANJIBINGBAOKUODANBUZHISHIGONGJINGAI。

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华夏棋牌MUQIANGUOJISHANGYOUSANZHONGHPVYIMIAO:

1. 二价HPV疫苗(Cervarix):针对HPV 16型和18型。

2. 四价HPV疫苗(Gardasil):针对HPV 6、11、16和18型。

3. 九价HPV疫苗(Gardasil 9):针对HPV 6、11、16、18、31、33、45、52和58型。

ZAIQUANQIUFANWEINEILAISHUO,DAYUEYOU70%DEGONGJINGAI、JIANGJIN90%DEGANGMENAIHEHENDABILIDEKOUYANAI、WAIYINAI、YINDAOAI、YINJINGAISHIYOUHPV 16HE18ZHEILIANGGEJIYINXINGDAOZHIDE(SANZHONGHPVYIMIAODOUBAOHANZHEILIANGGEJIYINXING);YOU20%GONGJINGAISHIYOUHPV 31、33、45、52HE58XINGDAOZHIDE(ZHIYOUJIUJIAYIMIAOBAOHANZHEIJIGEJIYINXING);HPV 6XINGHE11XINGZEDAOZHILEYUE90%DEGANGMENSHENGZHIQIYOU(SIJIAHEJIUJIAYIMIAODOUBAOHANZHEILIANGGEJIYINXING)。

四价和九价HPV疫苗除了预防宫颈癌以外,还可以预防肛门生殖器疣(约90%的肛门生殖器疣是由四价和九价疫苗包含的HPV 6型和11型导致的)。

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华夏棋牌UpToDateSHUO,“RUGUOMEIYOUHUAFEIHEKEYONGXINGFANGMIANDEWENTI,WOMENTUIJIANJIEZHONGJIUJIAYIMIAO。”“XIANGBIYUSIJIAHEERJIAYIMIAO,JIUJIAYIMIAOFUGAIDEHPVYAXINGGENGDUO,YINCINENGYUFANGGENGDUODEGONGJINGAI。”

SUOYI,JIUJIAYIMIAOBISIJIAHEERJIAYIMIAOHAOYINGGAISHIMEISHENMEYIYIDE(ZAIQIANGDIAOYICI,BENWENBUKAOLVJIAGEWENTI)。

NEIMESIJIAYIMIAOHEERJIAYIMIAONAGEGENGHAONI?

华夏棋牌YOUYANJIUBIAOMING,ERJIAYIMIAOYOUDAOCHUZHENDUIHPV 16XINGHE18XINGDEXUEQINGZHONGHEKANGTIGMT(JIHEPINGJUNDIDU)FENBIESHISIJIAYIMIAODE2.3~4.8BEIHE6.8~9.1BEI,SUOYIKEYIZHENGMINGERJIAYIMIAOYUFANGGONGJINGAIDEXIAOGUOBISIJIAYIMIAOHAOMA?——BUYIDING,YINWEIYOUDAOCHUZHENDUIHPV 16XINGHE18XINGDEGENGGAOXUEQINGDIDUNENGFOUYINGXIANGMIANYIBAOHUDECHENGDUHECHIXUSHIJIAN,MUQIANHAIBUQINGCHU。

二价疫苗和四价疫苗对HPV 16型和18型都有高保护力,两种疫苗诱导出的抗体滴度都远高于自然感染的抗体滴度。

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华夏棋牌ERJIAHPVYIMIAOSHIGSK(GELANSUSHIKE)GONGSIDECHANPIN,GSKSHIYIJIAYINGGUOGONGSI。SIJIAHEJIUJIAYIMIAODOUSHIMSD(MOSHADONG)GONGSIDECHANPIN,MOSHADONGSHIYIJIAMEIGUOGONGSI。MUQIANYINGGUOZHENGFUDEHPVYIMIAOJIEZHONGJIHUASHIYONGDESHIMEIGUOGONGSIDESIJIAYIMIAO,ERBUSHIBENGUOGONGSIDEERJIAYIMIAO。ANDAOLISHUO,WULUNSHICAIGOUJIAGEFANGMIANHAISHIGONGHUOBAOZHENGFANGMIAN,BENGUOGONGSIYINGGAIDOUYOUMINGXIANYOUSHI,DANYINGGUOZHENGFUHAISHIXUANZELEMEIGUOGONGSIDESIJIAYIMIAO,HENMINGXIANJIUSHIYINWEISIJIAYIMIAOBIERJIAYIMIAOHAO。

至于英国政府为什么不选择九价疫苗,最大的可能是因为九价疫苗太贵了,其次可能也担心九价疫苗供货不足。

所以,我的观点是,对个体而言,HPV疫苗的优先选择顺序为:九价疫苗>四价疫苗>二价疫苗。

华夏棋牌DANSHI,ZAIGUONEIJIEZHONGDEHUA,HAIHUISHOUDAOGUONEISHUOMINGSHUDENIANLINGXIANZHI。ZAIGUONEIDESHUOMINGSHUZHONG,ERJIAYIMIAOTUIJIANYONGYU9~25SUIDENVXING,SIJIAYIMIAOSHIYONGYU20~45SUINVXING。JIUJIAYIMIAOHUOPIZHUNDESHIYONGRENQUNZESHI16~26SUINVXING。SUOYI,ZAIGUONEIJIEZHONGDEHUA,9~15SUIZHINENGJIEZHONGERJIAYIMIAO,27~45SUIZHINENGJIEZHONGSIJIAYIMIAO,QITAZHONGDIEDENIANLINGCAIYOUDEXUANZE。

CANKAOZILIAO:

华夏棋牌1. J Thomas Cox. RENRUTOULIUBINGDUYIMIAOJIEZHONG. UpToDateLINCHUANGGUWEN. (Accessed on May 16, 2018).

2. SHIWEIZUZHI. RENRUTOULIUBINGDUYIMIAOSHIJIEWEISHENGZUZHILICHANGWENJIAN(2014NIAN10YUE).

华夏棋牌3. SHIWEIZUZHI. Human papillomavirus vaccines: WHO position paper, May 2017.

4. NHS choices. HPV vaccine. http://www.nhs.uk/conditions/vaccinations/hpv-human-papillomavirus-vaccine/ (Accessed on May 16, 2018).

5. Daniela A Carusi. WAIYINHEYINDAOYOUDEZHILIAO. UpToDateLINCHUANGGUWEN. (Accessed on May 16, 2018).

6. GUOJIAYAOJIANGUANLIJU. JIUJIARENRUTOUZHUANGLIUBINGDUYIMIAOYOUTIAOJIANPIZHUNSHANGSHI. http://cnda.cfda.gov.cn/WS04/CL2056/227881.html (Accessed on May 16, 2018).


SHANGQIUZHONGTIESHIJUYIYUAN(YUANSANJUYIYUAN)HPVJISHUYINGYONGZHONGXINSHISHANGQIUSHIYIYUANNEIZHUANYEFANGZHIHPV(RENRUTOULIUBINGDU)、JIANRUISHIYOUDEKESHI,ZHUZHIHPVGONGJINGSHANGPINEILIUBIAN CIN 1JI,CIN 2JI ,JIANRUISHIYOUDENGHPVGANRANXINGJIBING。

华夏棋牌GAIKEYUBEIJINGZHONGYIYAODAXUE,BEIJINGZHONGYIYANJIUYUAN,XIANYANGSENXINSHENGWUKEJIYOUXIANGONGSISHENGLUKEJIQIANGQIANGLIANHE,ZHILIYUHPVLVSELIAOFAZAIYUDONGDIQUDEPUJIHETUIGUANG。

关键词: HPV疫苗该如何选择   HPV疫苗选择